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Today: Aug 17, 2019

Metromom®

Metronidazole BP 200 mg

COMPOSITION
Metromom® Suspension : Each 5 ml contains Benzoyl Metronidazole equivalent to Metronidazole BP 200 mg.


PHARMACOLOGY
Metromom® (Metronidazole), a nitroimidazole has an extremely broad spectrum antiprotozoal and antimicrobial activities, with high activity against anaerobic bacteria and protozoa. Metromom® (Metronidazole) is usually completely and rapidly absorbed after oral administration. The half-life in plasma is about 8 hours. About 10% of the drug is bound to plasma proteins. Metromom® (Metronidazole) penetrates well into body tissues and fluids. The liver is the main site of metabolism. Both unchanged Metronidazole and metabolites are excreted in various proportions in the urine after oral administration.

 

INDICATION
All forms of amoebiasis (intestinal and extra-intestinal disease including liver abscess and that of symptomless cyst passers) Trichomoniasis Giardiasis Bacterial vaginosis Acute ulcerative gingivitis Anaerobic infections including septicaemia, bacteraemia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis etc. Anaerobically-infected leg ulcers and pressure sores Acute dental infections (e.g. acute pericoronitis and acute apical infections) Surgical prophylaxis (prevention of postoperative infections due to anaerobic bacteria, particularly species of bacteroides and anaerobic streptococci Chronic symptomatic peptic ulcer disease (as an agent of triple therapy to eradicate H. pylori-the most important aetiological factor of peptic ulcer)

 

ADVERSE REACTION
Metalic taste, furred tongue, nausea, vomiting, diarrhoea, drowsiness, rashes and mild reversible leucopenia may be observed during treatment.

 

DRUG INTERACTION
Metronidazole interacts with warfarin, nicoumalone, phenytoin, phenobarbitone, fluorouracil, disulfiram, lithium, cimetidine etc.

 

PREGNANCY & LACTATION
Not recommended during first & later trimesters. Breast feeding should be delayed until 48 hours
after discontinuing metronidazole in the mother.

 

STORAGE CONDITION
Store in a cool and dry place. Protect from light. Keep out of the reach of children.

 

DOSAGE & ADMINISTRATION

If not otherwise prescribed by the physician the following dosage schedule may be followed :

 

Indication

Duration

of dosage

in days

Children

7-10 years

3-7 years

1-3 years

Trichomoniasis**

7

100 mg t.i.d.

100 mg t.i.d.

50 mg t.i.d.

Invasive intestinal amoebiasis

5

400 mg t.i.d.

200 mg t.i.d.

200 mg t.i.d.

Extra intestinal amoebiasis (including liver abscess) and symptomless amoebic cyst passers

5-10

200 -400 mg t.i.d

100 -200 mg t.i.d

100 -200 mg t.i.d

Giardiasis

3

1.0 gm once daily

600-800 mg

once daily

500 mg

once daily

Acute ulcerative gingivitis

3

100 mg t.i.d.

100 mg t.i.d.

50 mg t.i.d.

Anaerobic infections

7

7.5 mg/kg t.i.d.

7.5 mg/kg t.i.d.

7.5 mg/kg t.i.d.

Surgical prophylaxis

7.5 mg/kg t.i.d.

7.5 mg/kg t.i.d.

7.5 mg/kg t.i.d.

**Trichomoniasis: Concomitant treatment of sexual consorts is recommended.

 

HOW SUPPLIED
Metromom® Suspension :
Each Glass bottle contains 60 ml suspension with measuring cup.

 

Manufactured by :

MOMTAZ Pharmaceuticals Limited

 


Design & Developed at BD HOST IT.