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Today: Aug 17, 2019

PMOL®

Paracetamol BP 500mg

COMPOSITION
Suspension: Each 5 ml suspension contains Paracetamol BP 120 mg.

PHARMACOLOGY
Pmol® is the formulation of Paracetamol (Acetaminophen) which is one of the safest and most widely used analgesic and antipyretic. Pmol® produces analgesic action by elevation of the pain threshold and antipyresis through action on the hypothalamic heat regulating center. Pmol® exerts significantly milder side effects and most unlikely to produce many of the serious side effects associated with aspirin and other NSAIDs.


Paracetamol is rapidly and completely absorbed from the GIT following oral administration and from rectum after rectal administration. The mean half-life of absorption from the upper small intestine is only 7 minutes. The drug is extensively metabolized in the liver and it has a plasma half life of 1.5 to 3.0 hours. Paracetamol is not bound to plasma proteins to any extent.


INDICATION

  • Fever, common cold and influenza.
  • Headache, toothache, earache, bodyache, myalgia, dysmenorrhoea, neuralgia and sprains.
  • Pain of colic, back pain, post-operative pain, postpartum pain, chronic pain of cancer, inflammatory
    pain, and post-vaccination pain and fever of children.
  • Rheumatism and osteoarthritic pain & stiffness of joints in fingers, hips, knees, wrists, elbows, feet,
    ankles and top & bottom of the spine.


DOSAGE AND ADMINISTRATION

Suspension
Children under 3 months: 10 mg/kg body weight (reduce to 5 mg/kg if jaundiced) 3 to 4 times daily.
3 months to below 1 year: ½ to 1 teaspoonful 3 to 4 times daily. 1-5 years: 1-2 teaspoonful 3 to 4 times daily.
6-12 years: 2-4 teaspoonful 3 to 4 times daily. Adults: 4-8 teaspoonful 3 to 4 times daily.

CONTRAINDICATION
Known sensitivity to Paracetamol.


SIDE EFFECTS
Side effects are significantly mild, though haematological reactions have been reported. Pancreatitis, skin rashes, and other allergic reactions occur occasionally.

 

OVERDOSE

Moderate overdose : 4-10 gm/day.
Excessive overdose : More than 10 gm/day.


Symptoms of overdose include pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12-48 hours after ingestion. In severe poisoning hepatic failure may progress to encephalopathy, coma and death.

USE IN PREGNANCY & LACTATION
Paracetamol is safe in all stage of pregnancy and lactation.


STORAGE
Keep in a cool & dry place, protected from light and moisture.
Keep all medicines out of the reach of children.


HOW SUPPLIED
Pmol® Suspension : 60 ml suspension in sealed cap Glass bottle.


Manufactured by :

MOMTAZ Pharmaceuticals Limited

 


Design & Developed at BD HOST IT.